SCHEMBL6295396

SCHEMBL6295396

O=C(NSc1ccccc1)Nc1ccc(C(=O)NS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.50
MEN1 O00255 4/20 0.50
L3MBTL1 Q9Y468 2/20 0.48
P4HTM Q9NXG6 3/20 0.48
LMNA P02545 3/20 0.48
FLT1 P17948 2/20 0.48
FLT4 P35916 2/20 0.48
KDR P35968 2/20 0.48
HPGD P15428 1/20 0.48
PTGS2 P35354 2/20 0.47
PTGS1 P23219 1/20 0.47
BCL2L1 Q07817 2/20 0.45
MCL1 Q07820 2/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
BCL2 P10415 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7774533 0.93 L3MBTL1 (0.47) KMT2AMEN1L3MBTL1LMNAFLT1
SCHEMBL7643073 0.92 LMNA (0.60) KMT2AMEN1L3MBTL1LMNAFLT1
SCHEMBL7641936 0.89 ALDH1A1 (0.52) KMT2AMEN1L3MBTL1LMNAFLT1
SCHEMBL7776157 0.89 HSD17B10 (0.58) KMT2AMEN1P4HTMLMNABCL2L1
SCHEMBL8768272 0.88 GPR27 (0.51) KMT2AMEN1L3MBTL1P4HTMLMNA
SCHEMBL7776315 0.87 ALDH1A1 (0.48) KMT2AL3MBTL1LMNABCL2L1MCL1
SCHEMBL7776170 0.86 MAPT (0.51) KMT2AMEN1LMNAHPGDBCL2L1
SCHEMBL7776171 0.85 PTGES (0.44) KMT2AMEN1L3MBTL1HPGDBCL2L1
SCHEMBL6295675 0.85 SIRT1 (0.60) KMT2AMEN1L3MBTL1P4HTMLMNA
SCHEMBL8768060 0.81 KAT6A (0.51) KMT2AMEN1L3MBTL1LMNAFLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6921740-B1 Electron-receiving compound and thermal recording material MITSUBISHI PAPER MIILS LTD. (JP) 2005-07-26 US disclosed
EP-0863022-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2002-09-18 EP disclosed
EP-0788889-B1 A thermal sensitive recording sheet JUJO PAPER CO LTD (JP) 2001-08-08 EP disclosed
US-6028030-A CONTAINING AN IMAGE PRESERVATIVE/STABILIZER POLYUREA IN THE THERMAL COLOR DEVELOPING LAYER CONTAINING DYE PRECURSOR NIPPON PAPER INDUSTRIE CO., LTD. (JP) 2000-02-22 US disclosed
EP-0863022-A1 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1998-09-09 EP disclosed
EP-0788889-A2 A thermal sensitive recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-13 EP disclosed