Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HPGDS | O60760 | 2/20 | 0.62 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26319518 | 0.87 | ALDH1A1 (0.73) | ALDH1A1HPGDSPTPN1KDM4ENPC1 | |
| SCHEMBL2104811 | 0.87 | ALDH1A1 (0.73) | ALDH1A1HPGDSPTPN1KDM4ENPC1 | |
| SCHEMBL352152 | 0.87 | HPGDS (0.73) | ALDH1A1HPGDSPTPN1KDM4ENPC1 | |
| SCHEMBL1683594 | 0.85 | HDAC1 (0.64) | ALDH1A1HPGDSPTPN1KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL6821751 | 0.85 | HPGDS (0.71) | ALDH1A1HPGDSPTPN1KDM4ENPC1 | |
| SCHEMBL1785557 | 0.80 | ALDH1A1 (0.73) | ALDH1A1HPGDSPTPN1KDM4ENPC1 | |
| SCHEMBL9613348 | 0.80 | ALDH1A1 (0.72) | ALDH1A1HPGDSPTPN1KDM4ENPC1 | |
| SCHEMBL27768678 | 0.80 | HDAC1 (0.70) | ALDH1A1HPGDSKDM4ENPC1RAB9A | |
| SCHEMBL786711 | 0.79 | LMNA (0.56) | ALDH1A1HPGDSKDM4ENPC1RAB9A | |
| SCHEMBL24136179 | 0.79 | ALDH1A1 (0.71) | ALDH1A1HPGDSPTPN1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124957-A1 | PHOLASIN | University of Wales College of Medicine (GB) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000028025-A1 | PHOLASIN | UNIVERSITY OF WALES COLLEGE OF MEDICINE (GB) | 2000-05-18 | — | — | WO | disclosed |