Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775670 | 0.89 | PAOX (0.37) | TSHRKMT2AMEN1ACHEALDH1A1 | |
| SCHEMBL14001490 | 0.85 | MEN1 (0.38) | TSHRMAPK1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7778629 | 0.84 | ALDH1A1 (0.31) | TSHRKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL24040342 | 0.84 | CA2 (0.34) | TSHRKMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL13475343 | 0.83 | TSHR (0.40) | TSHRKMT2AMEN1ALDH1A1GAA | |
| SCHEMBL13018276 | 0.82 | GLP1R (0.36) | TSHRCYP2C19 | |
| SCHEMBL7713617 | 0.82 | ALDH1A1 (0.46) | TSHRMAPK1KMT2AMEN1ACHE | |
| SCHEMBL22561224 | 0.80 | ACHE (0.43) | TSHRKMT2AMEN1ACHEALDH1A1 | |
| SCHEMBL16303440 | 0.80 | TSHR (0.35) | TSHRMAPK1KMT2AMEN1RAB9A | |
| SCHEMBL1415972 | 0.80 | TSHR (0.35) | TSHRMAPK1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014131892-A1 | CELL-PENETRATING OLIGONUCLEOTIDES | OLIGOMER SCIENCES AB (SE) | 2014-09-04 | — | — | WO | disclosed |
| US-20140206570-A1 | Characterization of biochips containing self-assembled monolayers | THE UNIVERSITY OF CHICAGO (US) | 2014-07-24 | — | — | US | disclosed |
| US-20140134642-A1 | Characterization of biochips containing self-assembled monolayers | THE UNIVERSITY OF CHICAGO (US) | 2014-05-15 | — | — | US | disclosed |
| EP-0733045-B1 | 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2001-08-16 | — | — | EP | disclosed |
| EP-0733045-A1 | 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS | ZENECA LIMITED (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015952-A1 | 4,6-DIANILINO-PYRIMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS TYROSINE KINASE INHIBITORS | ZENECA LIMITED (GB) | 1995-06-15 | — | — | WO | disclosed |