Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713617 | 0.82 | ALDH1A1 (0.46) | TSHRMAPK1KMT2AMEN1ACHE | |
| SCHEMBL7778631 | 0.80 | TSHR (0.35) | TSHRMAPK1KMT2AMEN1RAB9A | |
| SCHEMBL16303440 | 0.80 | TSHR (0.35) | TSHRMAPK1KMT2AMEN1RAB9A | |
| SCHEMBL22561224 | 0.80 | ACHE (0.43) | TSHRKMT2AMEN1ACHEALDH1A1 | |
| SCHEMBL7778620 | 0.78 | RAB9A (0.34) | TSHRMAPK1KMT2AMEN1RAB9A | |
| SCHEMBL7771287 | 0.78 | NAAA (0.35) | TSHRMAPK1KMT2AMEN1RAB9A | |
| SCHEMBL1472209 | 0.78 | NAMPT (0.42) | TSHRKMT2AMEN1ALDH1A1FAAH | |
| SCHEMBL7775670 | 0.77 | PAOX (0.37) | TSHRKMT2AMEN1ACHEALDH1A1 | |
| SCHEMBL23051922 | 0.76 | EPHX2 (0.41) | TSHRMAPK1KMT2AMEN1ACHE | |
| SCHEMBL7776039 | 0.76 | LGALS1 (0.46) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2165830-B1 | Lithographic printing plate precursor and printing method using the same | FUJIFILM CORP (JP) | 2011-03-16 | — | — | EP | disclosed |
| US-20100071574-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| EP-2165830-A1 | Lithographic printing plate precursor and printing method using the same | Fujifilm Corporation (JP) | 2010-03-24 | — | — | EP | disclosed |