SCHEMBL777982

SCHEMBL777982

CCS(=O)(=O)c1ccccc1F

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 2/20 0.48
KMT2A Q03164 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
KCNA5 P22460 1/20 0.43
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
HSD11B1 P28845 1/20 0.41
GBA1 P04062 1/20 0.41
HSD17B10 Q99714 2/20 0.41
ALOX5AP P20292 1/20 0.40
FEN1 P39748 1/20 0.40
KAT6A Q92794 1/20 0.40
HCRTR2 O43614 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28680071 0.83 PSIP1 (0.59) PSIP1ALDH1A1TSHRHSD11B1
SCHEMBL776476 0.83 PTGES2 (0.44) PSIP1KMT2ATDP1HSD17B10ALOX5AP
SCHEMBL17384549 0.81 SLC40A1 (0.42) PSIP1KMT2ATDP1ALDH1A1TSHR
SCHEMBL9704703 0.80 KCNA5 (0.42) KMT2ATDP1KCNA5ALDH1A1HSD11B1
SCHEMBL777992 0.77 HSD11B1 (0.41) KMT2ATDP1KCNA5HSD11B1GBA1
SCHEMBL4178510 0.77 KCNA5 (0.40) KMT2ATDP1KCNA5GBA1KAT6A
SCHEMBL514170 0.76 ALDH1A1 (0.44) PSIP1KMT2ATDP1KCNA5ALDH1A1
SCHEMBL250919 0.75 AKR1B1 (0.53) KMT2AKCNA5HSD11B1KAT6A
SCHEMBL30333632 0.75 AKR1B1 (0.53) KMT2AKCNA5HSD11B1KAT6A
SCHEMBL29965315 0.75 NFE2L2 (0.44) KMT2ATDP1KCNA5ALDH1A1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-20230163345-A1 LITHIUM FLUORIDE-BASED AND RELATED CATHODE COMPOSITIONS AND BATTERIES COMPRISING THE SAME SILA NANOTECHNOLOGIES, INC. 2023-05-25 US disclosed
US-11552328-B2 Lithium battery cell including cathode having metal fluoride core-shell particle SILA NANOTECHNOLOGIES, INC. (US) 2023-01-10 US disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
US-11283107-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-22 US disclosed
US-20200235420-A1 LITHIUM FLUORIDE-BASED AND RELATED CATHODE COMPOSITIONS AND BATTERIES COMPRISING THE SAME SILA NANOTECHNOLOGIES, INC. 2020-07-23 US disclosed
EP-3621141-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2020-03-11 EP disclosed
CN-110198941-A Pyrrolopyridine N- oxidized derivatives and its preparation method and application 江苏豪森药业集团有限公司 2019-09-03 CN disclosed
US-20190229372-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2019-07-25 US disclosed
US-10333172-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2019-06-25 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120165309-A1 HETERO RING DERIVATIVE ASTELLAS PHARMA INC. (JP) 2012-06-28 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed
WO-2011158149-A1 2-(3,5-DISUBSTITUTEDPHENYL)PYRIMIDIN-4(3H)-ONE DERIVATIVES PFIZER INC. (US) 2011-12-22 WO disclosed
CN-101679311-A Quinazoline compound WYETH CORP 2010-03-24 CN disclosed
US-20090325065-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2009-12-31 US disclosed
CN-101541751-A Quinoline compounds WYETH CORP (US) 2009-09-23 CN disclosed
US-7504391-B2 Selective D1/D5 receptor antagonists for the treatment of obesity and CNS disorders SCHERING CORPORATION (US) 2009-03-17 US disclosed
EP-2012386-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY Mitsubishi Chemical Corporation (JP) 2009-01-07 EP disclosed
CN-101018773-A Heteroaryl benzamide derivatives for use as GLK activators in the treatment of diabetes ASTRAZENECA AB (SE) 2007-08-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165309-A1 HETERO RING DERIVATIVE IL2, PIK3R2, IL2RA PSIP1 3985/4885KMT2A 1656/4885TDP1 4159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.