Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777982 | 0.80 | PSIP1 (0.48) | KCNA5ALDH1A1HSD11B1GBA1KMT2A | |
| SCHEMBL9739903 | 0.76 | KMT2A (0.44) | KCNA5ALDH1A1HSD11B1GBA1KMT2A | |
| SCHEMBL777992 | 0.75 | HSD11B1 (0.41) | KCNA5HSD11B1GBA1KMT2ATDP1 | |
| SCHEMBL4178510 | 0.75 | KCNA5 (0.40) | KCNA5GBA1KMT2ATDP1NFE2L2 | |
| SCHEMBL1299168 | 0.75 | KAT6A (0.46) | KCNA5ALDH1A1HSD11B1GBA1KMT2A | |
| SCHEMBL9704080 | 0.74 | PLCG1 (0.69) | KMT2ATDP1AKR1B1PLCG1L3MBTL1 | |
| SCHEMBL9703985 | 0.74 | KEAP1 (0.46) | ALDH1A1HSD11B1KMT2ATDP1NFE2L2 | |
| SCHEMBL250919 | 0.74 | AKR1B1 (0.53) | KCNA5HSD11B1KMT2ANFE2L2KAT6A | |
| SCHEMBL30333632 | 0.74 | AKR1B1 (0.53) | KCNA5HSD11B1KMT2ANFE2L2KAT6A | |
| SCHEMBL29965315 | 0.74 | NFE2L2 (0.44) | KCNA5ALDH1A1HSD11B1GBA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470543-A1 | Heterocyclic imidazoles, remedies containing them and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-02-12 | — | — | EP | disclosed |