Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5861610 | 0.94 | POLB (0.43) | ALDH1A1KDM4EPOLBGPR119KMT2A | |
| SCHEMBL7787285 | 0.81 | TRPM8 (0.45) | ALDH1A1KDM4EPOLBRAB9AFDPS | |
| SCHEMBL7780059 | 0.79 | RAB9A (0.43) | ALDH1A1KDM4EKMT2ARAB9AFDPS | |
| SCHEMBL7788753 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4EPOLBRAB9AFDPS | |
| SCHEMBL5861519 | 0.77 | TRPM8 (0.47) | ALDH1A1KDM4EKMT2ARAB9AFDPS | |
| SCHEMBL5860443 | 0.76 | L3MBTL1 (0.41) | ALDH1A1KDM4EKMT2AHPGDRAB9A | |
| SCHEMBL5140898 | 0.76 | CYP1A2 (0.48) | ALDH1A1KDM4EKMT2ARAB9AFDPS | |
| SCHEMBL5862781 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2ARAB9AFDPS | |
| SCHEMBL5861527 | 0.75 | RAB9A (0.46) | ALDH1A1KDM4EPOLBKMT2ARAB9A | |
| SCHEMBL5861419 | 0.74 | MAPT (0.40) | ALDH1A1KDM4EPOLBKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140784-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2001-10-10 | — | — | EP | claimed |
| WO-2000037422-A2 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-06-29 | — | — | WO | claimed |