Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785046 | 0.93 | TDP1 (0.49) | SIGMAR1TDP1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7780342 | 0.84 | KMT2A (0.54) | TDP1ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL7780393 | 0.84 | SLC6A3 (0.46) | SIGMAR1ALDH1A1LMNATSHR | |
| SCHEMBL7787602 | 0.82 | ALDH1A1 (0.44) | TDP1ALDH1A1LMNAKMT2AGAA | |
| SCHEMBL7787942 | 0.82 | TDP1 (0.49) | TDP1ALDH1A1LMNAKMT2AGAA | |
| SCHEMBL7785132 | 0.81 | SIGMAR1 (0.48) | SIGMAR1TDP1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL7785210 | 0.81 | SIGMAR1 (0.43) | SIGMAR1TDP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7785087 | 0.81 | RAB9A (0.52) | SIGMAR1ALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL7789351 | 0.81 | TDP1 (0.41) | TDP1ALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL7780357 | 0.80 | TDP1 (0.47) | TDP1ALDH1A1LMNAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |