Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785656 | 0.92 | ALDH1A1 (0.62) | ALDH1A1GAALMNAKMT2ATP53 | |
| SCHEMBL7789410 | 0.91 | ALDH1A1 (0.57) | ALDH1A1GAALMNAKMT2ATP53 | |
| SCHEMBL7784878 | 0.90 | ALDH1A1 (0.68) | ALDH1A1GAALMNAKMT2ATP53 | |
| SCHEMBL27553461 | 0.85 | ALDH1A1 (0.64) | ALDH1A1GAALMNAKMT2ATP53 | |
| SCHEMBL7787655 | 0.84 | ALDH1A1 (0.44) | ALDH1A1GAALMNAKMT2ATP53 | |
| SCHEMBL7780560 | 0.84 | ALDH1A1 (0.44) | ALDH1A1GAALMNAKMT2ATP53 | |
| Hydrochloric Acid SCHEMBL7785398 | 0.81 | ALDH1A1 (0.79) | ALDH1A1GAALMNAKMT2ATP53 | |
| SCHEMBL7785458 | 0.81 | ALDH1A1 (0.64) | ALDH1A1GAALMNAKMT2ATP53 | |
| SCHEMBL7780313 | 0.81 | TDP1 (0.41) | ALDH1A1GAALMNAKMT2ATP53 | |
| SCHEMBL7789205 | 0.80 | GPR88 (0.48) | ALDH1A1GAALMNAKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |