Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785656 | 0.92 | ALDH1A1 (0.62) | ALDH1A1GAALMNACYP3A4KMT2A | |
| SCHEMBL7780394 | 0.91 | ALDH1A1 (0.67) | ALDH1A1GAALMNACYP3A4KMT2A | |
| SCHEMBL7787169 | 0.89 | ALDH1A1 (0.58) | ALDH1A1GAALMNACYP3A4KMT2A | |
| SCHEMBL7789205 | 0.87 | GPR88 (0.48) | ALDH1A1GAALMNACYP3A4KMT2A | |
| SCHEMBL7789413 | 0.86 | RXFP1 (0.44) | ALDH1A1GAALMNACYP3A4KMT2A | |
| SCHEMBL7787667 | 0.85 | MAPKAPK2 (0.46) | ALDH1A1GAALMNACYP3A4KMT2A | |
| SCHEMBL7787621 | 0.82 | KMT2A (0.43) | ALDH1A1GAALMNACYP3A4KMT2A | |
| SCHEMBL7785275 | 0.82 | ADRB3 (0.46) | ALDH1A1GAALMNAKMT2AMEN1 | |
| SCHEMBL7785458 | 0.81 | ALDH1A1 (0.64) | ALDH1A1GAALMNACYP3A4KMT2A | |
| SCHEMBL7780340 | 0.80 | KMT2A (0.42) | ALDH1A1GAALMNACYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |