Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28746788 | 0.83 | SLC6A2 (0.41) | IDO1TDO2CASRLMNAGAA | |
| SCHEMBL7780426 | 0.83 | SLC6A2 (0.41) | IDO1TDO2CASRLMNAGAA | |
| SCHEMBL7780080 | 0.83 | ALDH1A1 (0.46) | KRASSOS1CASRLMNANPC1 | |
| SCHEMBL7787788 | 0.82 | CASR (0.37) | IDO1TDO2CASRLMNAGAA | |
| SCHEMBL7780790 | 0.82 | ALDH1A1 (0.50) | KRASSOS1CASRLMNAGAA | |
| SCHEMBL27530316 | 0.82 | ALDH1A1 (0.50) | KRASSOS1CASRLMNAGAA | |
| SCHEMBL7785107 | 0.82 | ALDH1A1 (0.50) | KRASSOS1CASRLMNAGAA | |
| SCHEMBL7780773 | 0.81 | SMN1; SMN2 (0.43) | LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7787608 | 0.81 | MAPKAPK2 (0.40) | LMNASMN1; SMN2GAAALDH1A1SLC6A2 | |
| SCHEMBL7784937 | 0.78 | KRAS (0.37) | KRASSOS1CASRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |