Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786289 | 0.91 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AMCL1PTGS2 | |
| SCHEMBL7784898 | 0.90 | MEN1 (0.41) | ALDH1A1MEN1KMT2AMCL1ACLY | |
| SCHEMBL7784857 | 0.82 | MEN1 (0.43) | ALDH1A1MEN1KMT2AMAPTMCL1 | |
| SCHEMBL8662561 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AMCL1KDM4E | |
| SCHEMBL7784695 | 0.72 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPTAPEX1 | |
| SCHEMBL9221279 | 0.70 | MCL1 (0.46) | ALDH1A1MEN1KMT2AMCL1KDM4E | |
| SCHEMBL7782943 | 0.69 | MAOA (0.46) | ALDH1A1MEN1KMT2AMAPTMCL1 | |
| SCHEMBL2381428 | 0.69 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2AMAPTAPEX1 | |
| SCHEMBL9219554 | 0.69 | MCL1 (0.45) | ALDH1A1MEN1KMT2AMCL1PTGS2 | |
| SCHEMBL9226666 | 0.68 | VCAM1 (0.49) | ALDH1A1MEN1KMT2AMAPTMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | claimed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | claimed |
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |