Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782889 | 0.91 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACYP3A4MAPK1 | |
| SCHEMBL7784857 | 0.90 | MEN1 (0.43) | ALDH1A1MEN1KMT2AMCL1LMNA | |
| SCHEMBL7784898 | 0.89 | MEN1 (0.41) | ALDH1A1MEN1KMT2AMCL1PTGS2 | |
| SCHEMBL8662561 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AMCL1KDM4E | |
| SCHEMBL9221279 | 0.75 | MCL1 (0.46) | ALDH1A1MEN1KMT2AMCL1KDM4E | |
| SCHEMBL7786001 | 0.74 | KIF18A (0.46) | ALDH1A1MEN1KMT2ACYP3A4MAPK1 | |
| SCHEMBL9219554 | 0.73 | MCL1 (0.45) | ALDH1A1MEN1KMT2AMCL1PTGS2 | |
| SCHEMBL9226666 | 0.72 | VCAM1 (0.49) | ALDH1A1MEN1KMT2AMCL1PTGS2 | |
| SCHEMBL15996310 | 0.72 | MAOA (0.47) | ALDH1A1MEN1KMT2AMCL1KDM4E | |
| SCHEMBL10589478 | 0.72 | MCL1 (0.44) | ALDH1A1MEN1KMT2AMCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |