Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262282 | 0.85 | MTNR1A (0.44) | ALDH1A1SMN1; SMN2LMNATP53PARP1 | |
| SCHEMBL7242474 | 0.81 | LMNA (0.44) | ALDH1A1SMN1; SMN2LMNATP53PARP1 | |
| SCHEMBL8025254 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNATP53PARP1 | |
| SCHEMBL7980047 | 0.79 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNATP53NPC1 | |
| SCHEMBL7703944 | 0.78 | MTNR1A (0.40) | ALDH1A1SMN1; SMN2LMNATP53PARP1 | |
| SCHEMBL4701126 | 0.78 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2LMNATP53NPC1 | |
| SCHEMBL11541741 | 0.77 | MTNR1A (0.43) | ALDH1A1LMNAPARP1MTNR1AMTNR1B | |
| SCHEMBL5263397 | 0.77 | GLA (0.46) | ALDH1A1SMN1; SMN2LMNATP53MTNR1A | |
| SCHEMBL27577805 | 0.76 | LOXL2 (0.45) | ALDH1A1SMN1; SMN2LMNATP53HTR2C | |
| SCHEMBL8600117 | 0.76 | NPSR1 (0.49) | ALDH1A1SMN1; SMN2TP53MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144392-A1 | NOVEL TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000040568-A1 | NOVEL TETRAZOLINONE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (DE) | 2000-07-13 | — | — | WO | disclosed |