Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 2/20 | 0.51 |
| ▸ | PTP4A2 | Q12974 | 2/20 | 0.51 |
| ▸ | PTP4A1 | Q93096 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8842877 | 1.00 | PTP4A3 (0.51) | PTP4A3PTP4A2PTP4A1CYP3A4CYP1A2 | |
| SCHEMBL7793570 | 0.86 | MAPT (0.51) | CYP3A4CYP1A2CYP2C9CYP2B6CYP2D6 | |
| SCHEMBL8842889 | 0.84 | ALDH1A1 (0.47) | CYP1A2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL7784722 | 0.84 | ALDH1A1 (0.47) | CYP1A2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL8842926 | 0.81 | GAA (0.44) | CYP1A2MAPTGAAALDH1A1KDM4E | |
| SCHEMBL7784710 | 0.81 | GAA (0.44) | CYP1A2MAPTGAAALDH1A1KDM4E | |
| SCHEMBL2903666 | 0.80 | PTP4A3 (0.57) | PTP4A3PTP4A2PTP4A1CYP3A4CYP1A2 | |
| SCHEMBL7790430 | 0.78 | POLB (0.53) | KMT2AMAPTMEN1ALDH1A1KDM4E | |
| SCHEMBL7784713 | 0.78 | HDAC1 (0.48) | KMT2AMAPTALDH1A1LMNAHPGD | |
| SCHEMBL7784715 | 0.78 | HDAC1 (0.48) | KMT2AMAPTALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723969-B1 | Phosphonocarboxylic acid derivatives and their use in treating degenerative articular ailments | HOECHST AG (DE) | 2001-11-14 | — | — | EP | disclosed |
| US-5627173-A | Phosphonoacetic acid derivatives and their use for treating degenerative joint disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0723969-A1 | Phosphonocarboxylic acid derivatives and their use in treating degenerative articular ailments | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-31 | — | — | EP | disclosed |