SCHEMBL7784849

SCHEMBL7784849

[O-][S+](c1ccc(Cl)cc1)c1ccc(C(F)(F)F)[nH]1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7784932 0.72 KDM4E (0.32)
SCHEMBL548628 0.69 LMNA (0.50)
SCHEMBL9637022 0.69 LMNA (0.50)
SCHEMBL9635796 0.69 LMNA (0.50)
SCHEMBL7782874 0.66 MAPK14 (0.34) HSD17B2
SCHEMBL7784928 0.66 GCGR (0.50) HSD17B2
SCHEMBL7651489 0.64 LMNA (0.38)
SCHEMBL7937426 0.64 MAPT (0.41)
SCHEMBL3294173 0.63 KDM4E (0.37) HSD17B2
SCHEMBL9637222 0.63 CYP1A2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0801058-B1 Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents AMERICAN CYANAMID CO (US) 2001-10-10 EP disclosed