Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL54645 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2D6TRPA1HRH4KDM4E | |
| SCHEMBL30589180 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2D6TRPA1HRH4KDM4E | |
| SCHEMBL18269386 | 0.80 | KDM4E (0.33) | CYP1A2CYP2D6KDM4EALDH1A1MAPT | |
| SCHEMBL12863671 | 0.80 | MEN1 (0.40) | TRPA1MAPTMEN1USP2CYP3A4 | |
| SCHEMBL12960364 | 0.80 | HRH4 (0.39) | HRH4GAADRD2HTR2AHTR2C | |
| SCHEMBL10597663 | 0.75 | CYP1A2 (0.46) | CYP1A2CYP2D6TRPA1HRH4KDM4E | |
| SCHEMBL13926540 | 0.73 | TERT (0.36) | CYP1A2CYP2D6KDM4EALDH1A1LMNA | |
| SCHEMBL15704732 | 0.73 | CYP1A2 (0.36) | CYP1A2KDM4EALDH1A1TSHRHIF1A | |
| SCHEMBL16367800 | 0.70 | THRB (0.33) | THRB | |
| SCHEMBL16556384 | 0.69 | ACHE (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0704535-B1 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | BAYER AG (US) | 2001-11-28 | — | — | EP | claimed |
| EP-0704535-A2 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | Bayer Corporation (US) | 1996-04-03 | — | — | EP | claimed |
| US-5498542-A | Electrode mediators for regeneration of NADH and NADPH | BAYER CORPORATION (US) | 1996-03-12 | — | — | US | claimed |
| US-9688743-B2 | Optical biosensors | CARNEGIE MELLON UNIVERSITY (US) | 2017-06-27 | — | — | US | disclosed |
| US-20140193830-A1 | OPTICAL BIOSENSORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-07-10 | — | — | US | disclosed |
| US-8664364-B2 | Optical biosensors | CARNEGIE MELLON UNIVERSITY (US) | 2014-03-04 | — | — | US | disclosed |
| US-20110159519-A1 | OPTICAL BIOSENSORS | CARNEGIE MELLON UNIVERSITY (US) | 2011-06-30 | — | — | US | disclosed |
| EP-0704535-B1 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | BAYER AG (US) | 2001-11-28 | — | — | EP | disclosed |
| EP-0704535-A2 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | Bayer Corporation (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0704535-A2 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | Bayer Corporation (US) | 1996-04-03 | — | — | EP | disclosed |
| US-5498542-A | Electrode mediators for regeneration of NADH and NADPH | BAYER CORPORATION (US) | 1996-03-12 | — | — | US | disclosed |
| US-5498542-A | Electrode mediators for regeneration of NADH and NADPH | BAYER CORPORATION (US) | 1996-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110159519-A1 | OPTICAL BIOSENSORS | NCS1, MCU, LPO | CYP1A2 3695/4885CYP2D6 3107/4885TRPA1 469/4885 |
| US-20140193830-A1 | OPTICAL BIOSENSORS | NCS1, MCU, LPO | CYP1A2 3695/4885CYP2D6 3107/4885TRPA1 469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.