SCHEMBL7785605

SCHEMBL7785605

[CH2]CC(=O)OC(C)OCC

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2306711 0.82 LMNA (0.50) LMNAMGAMGAASIMGAM2
SCHEMBL106759 0.82 LMNA (0.50) LMNAMGAMGAASIMGAM2
SCHEMBL9598364 0.82 LMNA (0.50) LMNAMGAMGAASIMGAM2
SCHEMBL5512302 0.80 LMNA (0.48) LMNAMGAMGAASIMGAM2
SCHEMBL5512305 0.80 LMNA (0.48) LMNAMGAMGAASIMGAM2
SCHEMBL2304444 0.78 LMNA (0.53) LMNA
SCHEMBL5676038 0.78 TRPA1 (0.48) LMNAMGAMGAASIMGAM2
SCHEMBL5675738 0.78 LMNA (0.46) LMNAMGAMGAASIMGAM2
SCHEMBL8817117 0.78 ALDH1A1 (0.46) LMNA
SCHEMBL10565248 0.78 LMNA (0.46) LMNAMGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1137641-A1 PROCESS FOR PREPARING PYRIDAZIN-3-ON DERIVATIVES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2001-10-04 EP disclosed
WO-2000034249-A1 PROCESS FOR PREPARING PYRIDAZIN-3-ON DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-06-15 WO disclosed
WO-2000021936-A1 URACIL HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-04-20 WO disclosed