SCHEMBL2274133

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2273149	0.96	MEN1 (0.66)	MEN1KMT2AFFAR1ERO1AKDM4E
	SCHEMBL2271374	0.90	PYGL (0.67)	MEN1KMT2AFFAR1PYGLPYGM
	SCHEMBL2272594	0.89	PYGL (0.72)	MEN1KMT2AFFAR1PYGLPYGM
	SCHEMBL2271588	0.86	SERPINE1 (0.64)	MEN1KMT2APYGLPYGMSERPINE1
	SCHEMBL2276745	0.84	SERPINE1 (0.65)	MEN1KMT2APYGLPYGMSERPINE1
	SCHEMBL2270621	0.84	GALK1 (0.68)	PYGLPYGMSERPINE1NPC1
	SCHEMBL14075344	0.83	MEN1 (0.76)	MEN1KMT2AFFAR1ERO1AKDM4E
	SCHEMBL2271165	0.83	KDM4E (0.62)	MEN1KMT2AFFAR1KDM4EALDH1A1
	SCHEMBL2272043	0.83	SERPINE1 (0.75)	MEN1KMT2ASERPINE1ALDH1A1SMN1; SMN2
	SCHEMBL2271007	0.83	MEN1 (0.69)	MEN1KMT2APYGMSERPINE1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.