Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781187 | 0.90 | GAA (0.47) | LMNAITGB3ITGA2B | |
| SCHEMBL7785662 | 0.90 | MAPT (0.48) | LMNASMN1; SMN2ITGB3ITGA2BRAB9A | |
| SCHEMBL7790184 | 0.88 | MEN1 (0.48) | LMNASMN1; SMN2ITGB3ITGAVITGA2B | |
| SCHEMBL7194908 | 0.88 | ITGB3 (0.51) | LMNASMN1; SMN2ITGB3ITGAVITGA2B | |
| SCHEMBL7789975 | 0.87 | ITGB3 (0.46) | LMNAITGB3ITGAVITGA2B | |
| SCHEMBL7781212 | 0.87 | ITGB3 (0.48) | ITGB3ITGAVITGA2B | |
| SCHEMBL7788754 | 0.85 | ITGB3 (0.51) | ITGB3ITGAVITGA2B | |
| SCHEMBL7785609 | 0.85 | LMNA (0.45) | LMNASMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL7786217 | 0.84 | KMT2A (0.46) | LMNASMN1; SMN2ITGB3ITGAVITGA2B | |
| SCHEMBL7786246 | 0.83 | ITGB3 (0.46) | LMNASMN1; SMN2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |