Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7790034 | 0.87 | CAPN1 (0.48) | LMNAMEN1POLBKMT2ANPC1 | |
| SCHEMBL7782210 | 0.86 | DYRK1A (0.47) | DYRK1ADYRK1BPIN1ROCK2RPS6KA5 | |
| SCHEMBL7787034 | 0.80 | ALDH1A1 (0.47) | LMNAMEN1POLBKMT2ANPC1 | |
| SCHEMBL7787042 | 0.78 | DYRK1A (0.47) | DYRK1ADYRK1BPIN1MEN1KMT2A | |
| SCHEMBL7790079 | 0.78 | ROCK2 (0.43) | DYRK1ADYRK1BPIN1ROCK2RPS6KA5 | |
| SCHEMBL7787012 | 0.77 | ROCK2 (0.47) | DYRK1ADYRK1BPIN1ROCK2RPS6KA5 | |
| SCHEMBL7782141 | 0.76 | HPGDS (0.47) | DYRK1ADYRK1BPIN1ROCK2RPS6KA5 | |
| SCHEMBL7786987 | 0.76 | CAPN1 (0.45) | DYRK1ADYRK1BPIN1ROCK2RPS6KA5 | |
| SCHEMBL7782223 | 0.74 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL7380790 | 0.74 | LMNA (0.52) | PIN1LMNAMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |