SCHEMBL12955196

SCHEMBL12955196

Nc1ccc2cc(S(=O)(=O)O)cc(O)c2c1/N=N/c1cccc(S(=O)(=O)c2cccc(/N=N/c3c(N)ccc4cc(S(=O)(=O)O)cc(O)c34)c2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SENP2 Q9HC62 5/20 0.60
▸ SUMO2 P61956 3/20 0.60
▸ SUMO1 P63165 3/20 0.60
▸ SENP7 Q9BQF6 3/20 0.60
▸ MAPK1 P28482 3/20 0.55
▸ GAA P10253 1/20 0.55
▸ MAPT P10636 1/20 0.55
▸ KMT2A Q03164 1/20 0.55
▸ TDP1 Q9NUW8 1/20 0.55
▸ ENPP2 Q13822 2/20 0.52
▸ SENP1 Q9P0U3 4/20 0.50
▸ SENP3 Q9H4L4 3/20 0.50
▸ PHLPP2 Q6ZVD8 1/20 0.49
▸ APEX1 P27695 2/20 0.47
▸ CYP1A2 P05177 3/20 0.47
▸ GLO1 Q04760 3/20 0.46
▸ NT5E P21589 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.44
▸ CA12 O43570 1/20 0.42
▸ CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7790541 0.88 SENP2 (0.68) SENP2SUMO2SUMO1SENP7MAPK1
SCHEMBL7790539 0.88 SENP2 (0.68) SENP2SUMO2SUMO1SENP7MAPK1
SCHEMBL11670234 0.87 SUMO2 (0.74) SENP2SUMO2SUMO1SENP7MAPK1
SCHEMBL11670202 0.86 SUMO2 (0.72) SENP2SUMO2SUMO1SENP7MAPK1
SCHEMBL11765850 0.84 SUMO2 (0.81) SENP2SUMO2SUMO1SENP7ENPP2
SCHEMBL11765859 0.84 SUMO2 (0.81) SENP2SUMO2SUMO1SENP7ENPP2
SCHEMBL10941468 0.83 SUMO2 (0.72) SENP2SUMO2SUMO1SENP7MAPK1
SCHEMBL26459720 0.83 SUMO2 (0.72) SENP2SUMO2SUMO1SENP7KMT2A
SCHEMBL10941472 0.83 SUMO2 (0.72) SENP2SUMO2SUMO1SENP7MAPK1
SCHEMBL14418348 0.83 SUMO2 (0.72) SENP2SUMO2SUMO1SENP7KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2142011-B1 METHOD FOR MODULATING THE TASTE OF MATERIAL COMPISITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) 2011-01-12 — — EP disclosed
EP-2139347-B1 USE OF WATER-DISPERSIBLE CAROTINOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTINOID NANOPARTICLES, AND METHOD FOR TASTE MODULATION BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) 2011-01-12 — — EP disclosed
US-20100047426-A1 METHOD FOR MODULATING THE TASTE OF MATERIAL COMPOSITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) BASF SE (DE) 2010-02-25 — — US disclosed
US-20100047426-A1 METHOD FOR MODULATING THE TASTE OF MATERIAL COMPOSITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) BASF SE (DE) 2010-02-25 — — US disclosed
US-20100028444-A1 USE OF WATER-DISPERSIBLE CAROTENOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTENOID NANOPARTICLES, AND, METHOD FOR TASTE MODULATION BASF SE (DE) 2010-02-04 — — US disclosed
US-20100028444-A1 USE OF WATER-DISPERSIBLE CAROTENOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTENOID NANOPARTICLES, AND, METHOD FOR TASTE MODULATION BASF SE (DE) 2010-02-04 — — US disclosed
WO-2008102019-A2 USE OF WATER-DISPERSIBLE CAROTINOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTINOID NANOPARTICLES, AND METHOD FOR TASTE MODULATION BASF SE (DE) 2008-08-28 — — WO disclosed
WO-2008102018-A2 METHOD FOR MODULATING THE TASTE OF MATERIAL COMPISITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) BASF SE (DE) 2008-08-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100028444-A1 USE OF WATER-DISPERSIBLE CAROTENOID NANOPARTICLES AS TASTE MODULATORS, TASTE MODULATORS CONTAINING WATER-DISPERSIBLE CAROTENOID NANOPARTICLES, AND, METHOD FOR TASTE MODULATION TAS2R13, TAS2R10, TAS2R16 SENP2 4423/4885SUMO2 2454/4885SUMO1 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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