Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793613 | 0.83 | L3MBTL1 (0.45) | FDFT1KDM4EL3MBTL1POLBCA12 | |
| SCHEMBL7784734 | 0.82 | KMT2A (0.45) | FDFT1KDM4EPOLBMAPTGAA | |
| SCHEMBL7790656 | 0.77 | FDFT1 (0.68) | FDFT1CA12CA1CA2CA9 | |
| SCHEMBL8410675 | 0.76 | FFAR1 (0.46) | KDM4EPOLBEPHX2 | |
| SCHEMBL5366533 | 0.75 | FDPS (0.59) | POLBMAPTLMNA | |
| SCHEMBL21501951 | 0.74 | FDPS (0.39) | KDM4EPTPN2PTPN1L3MBTL1POLB | |
| SCHEMBL7793195 | 0.74 | KDM4E (0.44) | FDFT1KDM4EPTPN2PTPN1POLB | |
| SCHEMBL7793582 | 0.74 | KDM4E (0.43) | KDM4EPTPN2PTPN1L3MBTL1POLB | |
| SCHEMBL5363659 | 0.74 | RAB9A (0.49) | KDM4EL3MBTL1POLBMAPTLMNA | |
| SCHEMBL9274997 | 0.72 | HMGCR (0.38) | KDM4EPTPN2PTPN1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |
| EP-0762883-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1997-03-19 | — | — | EP | claimed |
| WO-1995033466-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1995-12-14 | — | — | WO | claimed |
| US-5866556-A | BONE DISORDERS | LEIRAS OY (FI) | 1999-02-02 | — | — | US | disclosed |