Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | AGXT | P21549 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 6/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31304968 | 0.91 | LOXL2 (0.51) | LOXL2ADRA2AAGXTHTR2BHTR1A | |
| SCHEMBL10366180 | 0.91 | LOXL2 (0.51) | LOXL2ADRA2AAGXTHTR2BHTR1A | |
| SCHEMBL2905181 | 0.88 | ADRA2A (0.46) | LOXL2ADRA2AAGXTHTR2BHTR1A | |
| SCHEMBL2906664 | 0.87 | VCP (0.45) | LOXL2ADRA2AAGXTHTR2BHTR1A | |
| SCHEMBL18528970 | 0.82 | LOXL2 (0.53) | LOXL2ADRA2AAGXTHTR2BHTR1A | |
| SCHEMBL1256835 | 0.77 | ADRA2A (0.58) | LOXL2ADRA2AAGXTBCHEACHE | |
| SCHEMBL1257003 | 0.76 | ADRA2A (0.57) | LOXL2ADRA2AAGXTHTR2BHTR1A | |
| SCHEMBL14075637 | 0.76 | LOXL2 (0.69) | LOXL2ADRA2AAGXTHTR2BHTR1A | |
| SCHEMBL3026368 | 0.72 | LOXL2 (0.64) | LOXL2ADRA2AAGXTHTR2BHTR1A | |
| SCHEMBL16549715 | 0.72 | LOXL2 (0.64) | LOXL2ADRA2AAGXTHTR2BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149085-A1 | AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS | ELI LILLY AND COMPANY (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000044737-A1 | AMINOALKYLBENZOFURANS AS SEROTONIN (5-HT(2C)) AGONISTS | ELI LILLY AND COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |