Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799269 | 0.88 | MTNR1A (0.45) | POLBCA2CA1CA5AMMP8 | |
| SCHEMBL7793398 | 0.86 | L3MBTL1 (0.46) | POLBCA2KMT2ACTSSCTSK | |
| SCHEMBL7798895 | 0.82 | NPC1 (0.50) | KMT2ACTSSCTSKMMP8 | |
| SCHEMBL7802324 | 0.82 | ITGB3 (0.48) | HPGD | |
| SCHEMBL7793458 | 0.82 | MMP1 (0.49) | POLBKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7798890 | 0.80 | NPC1 (0.48) | KMT2ACTSSCTSKMEN1ALDH1A1 | |
| SCHEMBL7793435 | 0.79 | CA12 (0.52) | POLBCA2CA1KMT2ACA5A | |
| SCHEMBL7803207 | 0.79 | POLB (0.43) | POLBCA2CA1KMT2ACA5A | |
| SCHEMBL7793421 | 0.79 | POLB (0.43) | POLBCA2CA1KMT2ACA5A | |
| SCHEMBL7798918 | 0.78 | POLB (0.42) | POLBCA2CA1KMT2ACA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143960-A2 | CYSTINE DERIVATIVES AS THERAPEUTIC AGENTS FOR MATRIX METALLOPROTEASE RELATED DISEASES | Roche Diagnostics GmbH (DE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000027378-A2 | CYSTINE DERIVATIVES AS THERAPEUTIC AGENTS FOR MATRIX METALLOPROTEASE RELATED DISEASES | ROCHE DIAGNOSTICS GMBH (DE) | 2000-05-18 | — | — | WO | disclosed |