Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8167824 | 0.84 | FDPS (0.44) | KDM4EEPHX2MEN1KMT2ALMNA | |
| SCHEMBL5366533 | 0.81 | FDPS (0.59) | LMNAPOLBFDPSNPSR1MAPT | |
| SCHEMBL9274896 | 0.75 | L3MBTL1 (0.38) | L3MBTL1GAACA12CA1CA2 | |
| SCHEMBL21501951 | 0.74 | FDPS (0.39) | KDM4EEPHX2L3MBTL1LMNAPTPN2 | |
| SCHEMBL7793634 | 0.74 | FDFT1 (0.42) | KDM4EEPHX2L3MBTL1LMNAPTPN2 | |
| SCHEMBL7793613 | 0.74 | L3MBTL1 (0.45) | KDM4EMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL5359859 | 0.73 | TSHR (0.42) | KDM4EMEN1KMT2AGAAPOLB | |
| SCHEMBL5360999 | 0.73 | FDPS (0.58) | KDM4EMEN1KMT2AL3MBTL1GAA | |
| SCHEMBL7784734 | 0.73 | KMT2A (0.45) | KDM4EMEN1KMT2ALMNAGAA | |
| SCHEMBL9602498 | 0.72 | KDM4E (0.46) | KDM4EEPHX2MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |
| EP-0762883-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1997-03-19 | — | — | EP | claimed |
| WO-1995033466-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1995-12-14 | — | — | WO | claimed |
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | disclosed |
| US-5866556-A | BONE DISORDERS | LEIRAS OY (FI) | 1999-02-02 | — | — | US | disclosed |
| US-5393748-A | Treating bone disorders, Paget* s disease, calcium metabolism disorders | LEIRAS OY (FI) | 1995-02-28 | — | — | US | disclosed |