Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793674 | 0.88 | L3MBTL1 (0.40) | L3MBTL1TSHRPPARGCA1CA2 | |
| SCHEMBL7784255 | 0.85 | L3MBTL1 (0.40) | L3MBTL1TSHRPPARGCA1CA2 | |
| SCHEMBL8103007 | 0.83 | FFAR4 (0.45) | TSHRPPARGALDH1A1PPARA | |
| SCHEMBL7784246 | 0.79 | L3MBTL1 (0.40) | L3MBTL1TSHRPPARGCA1CA2 | |
| SCHEMBL8104827 | 0.74 | TSHR (0.48) | L3MBTL1TSHRPPARGALDH1A1LMNA | |
| SCHEMBL7784250 | 0.74 | LMNA (0.51) | TSHRALDH1A1LMNA | |
| SCHEMBL7792778 | 0.74 | CTSK (0.32) | TSHRLMNAEPHX2 | |
| SCHEMBL7794222 | 0.73 | DGKA (0.45) | L3MBTL1TSHRALDH1A1LMNAPLA2G2A | |
| SCHEMBL7793707 | 0.72 | TSHR (0.39) | L3MBTL1TSHRPPARGALDH1A1LMNA | |
| SCHEMBL22122660 | 0.71 | TSHR (0.58) | TSHRCA2ALDH1A1LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947503-B1 | 6,8-Dimethylmercaptooctanoic acid derivatives substituted on 6-S and/or 8-S by the 3-methylthiopropanoyl radical and pharmaceutical compositions for the treatment of cancerous tumours | GALDERMA RES & DEV (FR) | 2001-11-21 | — | — | EP | claimed |
| US-6117902-A | 6,8-dimercaptooctanoic acid derivatives substituted at the 6-S and/or 8-S position with the (3-methylthiopropanoyl) radical and pharmaceutical compositions intended for the treatment of cancerous tumors | GALDERMAN RESEARCH & DEVELOPMENT, S.N.C. SOPHIA ABTIPOLIS (FR) | 2000-09-12 | — | — | US | disclosed |