Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 8/20 | 0.42 |
| ▸ | PYGL | P06737 | 2/20 | 0.41 |
| ▸ | PYGM | P11217 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791600 | 0.83 | CRBN (0.49) | RIPK1PYGLPYGMCRBN | |
| SCHEMBL7791794 | 0.82 | RIPK1 (0.46) | RIPK1PYGLPYGMCRBN | |
| SCHEMBL8667968 | 0.82 | CA12 (0.48) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL7792280 | 0.79 | PYGL (0.58) | RIPK1PYGLPYGM | |
| SCHEMBL13007537 | 0.76 | SIRT2 (0.45) | SIRT2PYGLPYGMKMT2AMEN1 | |
| SCHEMBL7794597 | 0.75 | RIPK1 (0.40) | SIRT2RIPK1PYGLPYGM | |
| SCHEMBL7794448 | 0.74 | SIRT2 (0.53) | SIRT2KMT2AMEN1ALDH1A1KIF11 | |
| SCHEMBL7794446 | 0.74 | SIRT2 (0.53) | SIRT2KMT2AMEN1ALDH1A1KIF11 | |
| SCHEMBL4107609 | 0.74 | MTNR1A (0.62) | — | |
| SCHEMBL4107613 | 0.74 | MTNR1A (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659179-B1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | disclosed |