Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800946 | 0.84 | L3MBTL1 (0.49) | L3MBTL1NPSR1CTSKNPC1HDAC1 | |
| SCHEMBL7799736 | 0.80 | L3MBTL1 (0.40) | L3MBTL1NPSR1NPC1HDAC1HDAC3 | |
| SCHEMBL7797006 | 0.78 | L3MBTL1 (0.45) | L3MBTL1NPSR1CTSKHDAC1HDAC3 | |
| SCHEMBL20330727 | 0.71 | SYK (0.45) | L3MBTL1NPSR1CTSKHDAC1HDAC3 | |
| SCHEMBL7137802 | 0.70 | CTSK (0.44) | CTSKHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL4781274 | 0.69 | HDAC3 (0.48) | L3MBTL1CTSKNPC1HDAC1HDAC3 | |
| SCHEMBL7139858 | 0.69 | CTSS (0.43) | L3MBTL1CTSKPPARACTSSCTSB | |
| SCHEMBL27460199 | 0.69 | MEN1 (0.42) | L3MBTL1NPSR1CTSKNPC1HDAC1 | |
| SCHEMBL3050230 | 0.68 | MEN1 (0.46) | L3MBTL1CTSKNPC1HDAC1HDAC3 | |
| SCHEMBL18845331 | 0.68 | HDAC3 (0.50) | L3MBTL1CTSKNPC1HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159260-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |