Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800925 | 0.89 | NPC1 (0.41) | SYKNPC1CTSSMEN1KMT2A | |
| SCHEMBL7796787 | 0.80 | L3MBTL1 (0.40) | L3MBTL1SYKNPC1CTSSPPARA | |
| SCHEMBL7797006 | 0.77 | L3MBTL1 (0.45) | L3MBTL1NPSR1HDAC3HDAC1HDAC2 | |
| SCHEMBL7797008 | 0.76 | MAPT (0.39) | L3MBTL1SYKHDAC3HDAC1HDAC2 | |
| SCHEMBL7131218 | 0.75 | PPARA (0.51) | L3MBTL1SYKNPC1CTSSPPARA | |
| SCHEMBL7137802 | 0.74 | CTSK (0.44) | SYKCTSSPPARAHDAC3HDAC1 | |
| SCHEMBL7135516 | 0.73 | CTSS (0.55) | SYKCTSSPPARANPSR1PPARG | |
| SCHEMBL7135455 | 0.72 | CTSB (0.38) | CTSSMEN1KMT2ACTSB | |
| SCHEMBL7799740 | 0.71 | SYK (0.47) | SYKNPC1CTSSPPARAPPARG | |
| SCHEMBL6182061 | 0.70 | CTSS (0.54) | CTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159260-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |