Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 7/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763256 | 0.77 | KCNN4 (0.39) | ALDH1A1KCNN4KIF11LTA4HKCNH2 | |
| SCHEMBL46390 | 0.75 | ALDH1A1 (0.43) | ALDH1A1RECQLLTA4HTAAR1 | |
| SCHEMBL19614367 | 0.73 | KCNN4 (0.48) | ALDH1A1KCNN4KIF11TAAR1 | |
| SCHEMBL28124931 | 0.71 | KCNN4 (0.46) | KCNN4KIF11TAAR1 | |
| SCHEMBL1225190 | 0.71 | KCNN4 (0.46) | ALDH1A1KCNN4KIF11TAAR1 | |
| SCHEMBL8113702 | 0.70 | ALDH1A1 (0.41) | ALDH1A1RECQLKCNN4LTA4HKDM4E | |
| SCHEMBL4750696 | 0.70 | KCNN4 (0.44) | ALDH1A1KCNN4KIF11KDM4ETAAR1 | |
| Hydrochloric Acid SCHEMBL2810585 | 0.70 | KCNN4 (0.44) | KCNN4KIF11TAAR1 | |
| SCHEMBL17583102 | 0.69 | LMNA (0.43) | ALDH1A1RECQL | |
| SCHEMBL11053988 | 0.68 | ALDH1A1 (0.40) | ALDH1A1RECQLKIF11LTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115695-A1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(N+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | Monsanto Company (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018724-A1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(n+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | disclosed |