Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 5/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7880855 | 1.00 | ABCB1 (0.36) | ABCB1L3MBTL1CTSCBACE1BACE2 | |
| SCHEMBL7798759 | 0.81 | OPRM1 (0.39) | ABCB1L3MBTL1CTSCBACE1 | |
| SCHEMBL7861035 | 0.79 | MEN1 (0.49) | MMP3 | |
| SCHEMBL27736155 | 0.77 | CTSC (0.41) | ABCB1L3MBTL1CTSCBACE1BACE2 | |
| SCHEMBL7277577 | 0.77 | CTSC (0.41) | ABCB1L3MBTL1CTSCBACE1BACE2 | |
| SCHEMBL7855559 | 0.75 | PDE4A (0.44) | — | |
| SCHEMBL7887863 | 0.74 | CTSC (0.48) | CTSCBACE1BACE2 | |
| SCHEMBL7857632 | 0.74 | CTSC (0.48) | CTSCBACE1BACE2 | |
| SCHEMBL8098831 | 0.72 | L3MBTL1 (0.38) | ABCB1L3MBTL1BACE1BACE2 | |
| SCHEMBL8690915 | 0.71 | CTSC (0.48) | CTSCBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307049-B1 | USEFUL FOR TREATING HAIR LOSS IN MAMMALS, INCLUDING ARRESTING AND/OR REVERSING HAIR LOSS AND PROMOTING HAIR GROWTH. | THE PROCTER & GAMBLE CO. | 2001-10-23 | — | — | US | disclosed |
| US-6300341-B1 | USEFUL FOR TREATING HAIR LOSS IN MAMMALS, INCLUDING ARRESTING AND/OR REVERSING HAIR LOSS AND PROMOTING HAIR GROWTH; MAY ALSO BE USED FOR THERAPY OF MULTI-DRUG RESISTANCE, HUMAN IMMUNODEFICIENCY VIRUS (HIV), CARDIAC INJURY | THE PROCTER & GAMBLE CO. | 2001-10-09 | — | — | US | disclosed |
| US-20010012895-A1 | Heterocyclic 2-substituted ketoamides | MCIVER JOHN MCMILLAN (US) | 2001-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010012895-A1 | Heterocyclic 2-substituted ketoamides | TK2, SHMT2, CYC1 | ABCB1 828/4885L3MBTL1 243/4885CTSC 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.