Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 6/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | CTSE | P14091 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113847 | 0.89 | L3MBTL1 (0.37) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL7798759 | 0.78 | OPRM1 (0.39) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL27736155 | 0.77 | CTSC (0.41) | L3MBTL1BACE1BACE2ABCB1OPRM1 | |
| SCHEMBL7277577 | 0.77 | CTSC (0.41) | L3MBTL1BACE1BACE2ABCB1OPRM1 | |
| SCHEMBL4775283 | 0.75 | AGTR2 (0.39) | BACE1DRD2DRD3 | |
| SCHEMBL14555331 | 0.74 | CTSL (0.43) | OPRM1OPRL1 | |
| SCHEMBL2981071 | 0.74 | CTSL (0.43) | OPRM1OPRL1 | |
| SCHEMBL13567992 | 0.73 | L3MBTL1 (0.43) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL13567987 | 0.73 | L3MBTL1 (0.43) | L3MBTL1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL1584174 | 0.73 | CTSL (0.42) | DRD2DRD3OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545290-B1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMA CO LTD (JP) | 2000-08-23 | — | — | EP | disclosed |
| US-5550121-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| WO-1993011128-A1 | AMINOALKYLPYRROLIDINYLTHIOCARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-10 | — | — | WO | disclosed |
| EP-0545290-A1 | Aminoalkylpyrrolidinylthiocarbapenem derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-09 | — | — | EP | disclosed |