Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804376 | 0.92 | MAPK1 (0.41) | MAPK1KMT2AMEN1HTR4SIGMAR1 | |
| SCHEMBL7806697 | 0.79 | SIGMAR1 (0.34) | HTR4SIGMAR1OPRM1OPRD1 | |
| SCHEMBL4351591 | 0.76 | MAPK1 (0.41) | MAPK1KMT2AMEN1 | |
| SCHEMBL5415021 | 0.72 | MAPK1 (0.48) | MAPK1KMT2AMEN1SIGMAR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7805841 | 0.69 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL7804700 | 0.68 | MAPK1 (0.44) | MAPK1KMT2AMEN1ALDH1A1OPRM1 | |
| SCHEMBL5071115 | 0.67 | MAPK1 (0.46) | MAPK1KMT2AMEN1SIGMAR1 | |
| SCHEMBL7799394 | 0.67 | OPRM1 (0.31) | SIGMAR1HTTUSP2TSHRHSD17B10 | |
| SCHEMBL7808200 | 0.67 | OPRM1 (0.31) | SIGMAR1HTTUSP2TSHRHSD17B10 | |
| SCHEMBL7647959 | 0.67 | SMN1; SMN2 (0.38) | MAPK1KMT2AMEN1SIGMAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710662-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | SYNGENTA LTD (GB) | 2001-04-04 | — | — | EP | disclosed |
| EP-1018513-A2 | Quinolinecarboxylic acid derivatives | ZENECA LIMITED (GB) | 2000-07-12 | — | — | EP | disclosed |
| EP-0710662-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-05-08 | — | — | EP | disclosed |