Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | AMPD2 | Q01433 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805844 | 0.93 | SIGMAR1 (0.36) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7805841 | 0.91 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL7799242 | 0.79 | MAPK1 (0.38) | SIGMAR1HTR4OPRM1OPRD1 | |
| SCHEMBL8716683 | 0.71 | OPRM1 (0.36) | SIGMAR1OPRM1OPRD1 | |
| SCHEMBL7804376 | 0.71 | MAPK1 (0.41) | SIGMAR1HTR4OPRM1OPRD1 | |
| SCHEMBL7809891 | 0.70 | LMNA (0.33) | OPRM1OPRD1 | |
| SCHEMBL7805881 | 0.70 | ACHE (0.35) | OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7809740 | 0.67 | CHRNA7 (0.40) | — | |
| SCHEMBL8715017 | 0.67 | CHRM1 (0.32) | — | |
| SCHEMBL3408506 | 0.66 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710662-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | SYNGENTA LTD (GB) | 2001-04-04 | — | — | EP | disclosed |
| EP-1018513-A2 | Quinolinecarboxylic acid derivatives | ZENECA LIMITED (GB) | 2000-07-12 | — | — | EP | disclosed |
| EP-0710662-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-05-08 | — | — | EP | disclosed |