Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | F11 | P03951 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793390 | 0.91 | KMT2A (0.57) | L3MBTL1KMT2ANPC1RAB9ACTSL | |
| SCHEMBL7798889 | 0.88 | NPC1 (0.64) | L3MBTL1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7798884 | 0.85 | ALDH1A1 (0.58) | L3MBTL1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7793435 | 0.80 | CA12 (0.52) | KMT2ASMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL2246542 | 0.80 | TDP1 (0.56) | L3MBTL1CNR1TDP1 | |
| SCHEMBL28551980 | 0.79 | RAB9A (0.74) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7799262 | 0.78 | POLB (0.52) | KMT2ACYP2D6CYP2C19 | |
| SCHEMBL20777179 | 0.77 | L3MBTL1 (0.67) | L3MBTL1KMT2ACTSLCTSBCNR1 | |
| SCHEMBL20777238 | 0.77 | L3MBTL1 (0.67) | L3MBTL1KMT2ACTSLCTSBCNR1 | |
| SCHEMBL24119968 | 0.76 | NPC1 (0.60) | L3MBTL1KMT2ANPC1RAB9ACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143960-A2 | CYSTINE DERIVATIVES AS THERAPEUTIC AGENTS FOR MATRIX METALLOPROTEASE RELATED DISEASES | Roche Diagnostics GmbH (DE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000027378-A2 | CYSTINE DERIVATIVES AS THERAPEUTIC AGENTS FOR MATRIX METALLOPROTEASE RELATED DISEASES | ROCHE DIAGNOSTICS GMBH (DE) | 2000-05-18 | — | — | WO | disclosed |