SCHEMBL7801205

SCHEMBL7801205

O=S(=O)(CCCl)CC[N]c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.32
POLB P06746 1/20 0.32
CYP2D6 P10635 1/20 0.32
ALDH1A1 P00352 3/20 0.30
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7756158 0.89 CA2 (0.33) CA2POLBCYP2D6
SCHEMBL7840761 0.88 KEAP1 (0.36) CA2
SCHEMBL7842624 0.86 KEAP1 (0.36) CA2
SCHEMBL7840304 0.84 ALDH1A1 (0.33) CA2CYP2D6ALDH1A1TDP1MEN1
SCHEMBL7803206 0.80 POLB (0.42) POLBCYP2D6ALDH1A1TDP1MEN1
SCHEMBL7841062 0.78 PTGS2 (0.41) CA2ALDH1A1MEN1LMNAMAPT
SCHEMBL7803303 0.78 SENP3 (0.41) CA2POLBCYP2D6ALDH1A1HSD17B10
SCHEMBL7837634 0.76 KEAP1 (0.33) ALDH1A1MAPT
SCHEMBL9639842 0.75 ALDH1A1 (0.41) ALDH1A1TDP1KDM4EMEN1LMNA
SCHEMBL1720603 0.75 POLB (0.42) CA2POLBCYP2D6ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675172-B1 Water-solable azo compounds, process for their preparation and their use as dyestuffs DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-04-11 EP disclosed
EP-0688831-B1 Watersoluble anthraquinone compounds, process for their manufacturing and their use as dyestuffs DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-04-04 EP disclosed
EP-0872523-A2 Fiber-reactive azo dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-10-21 EP disclosed
EP-0538785-B1 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AG (DE) 1997-04-09 EP disclosed
US-5610298-A Water-soluble anthraquinone compounds, preparation thereof and use thereof as dyes HOECHST AKTIENGESELLSCHAFT (DE) 1997-03-11 US disclosed
US-5539109-A Fiber-reactive triphenodioxazine dyes HOECHST CELANESE CORPORATION (US) 1996-07-23 US disclosed
US-5539088-A PROVIDE DYEINGS IN BRILLIANT SHADES WITH GOOD FASTNESS PROPERTIES AND HIGH DEGREE OF FIXATION HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-23 US disclosed
EP-0688831-A1 Watersoluble anthraquinone compounds, process for their manufacturing and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-27 EP disclosed
EP-0679696-A1 Water-soluble pyridone-disazo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-02 EP disclosed
EP-0675172-A2 Water-solable azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-04 EP disclosed
US-5280110-A Fiber-reactive dye HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-18 US disclosed
EP-0471702-B1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AG (DE) 1993-12-29 EP disclosed
US-5256776-A Brilliant green dyeings; fiber reactive HOECHST AKTIENGESELLSCHAFT (DE) 1993-10-26 US disclosed
US-5231172-A Water solubility HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-27 US disclosed
US-5227475-A WATER-SOLUBLE FIBER-REACTIVE DYESTUFFS CONTAINING A CYANAMIDO-SUBSTITUTED TRIAZINYLAMINO-GROUPING, AND A PROCESS FOR DYEING WITH THE USE OF THESE DYES HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-13 US disclosed
EP-0548792-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0538785-A2 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-28 EP disclosed
EP-0530660-A2 Water-soluble phthalocyanine dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-10 EP disclosed
WO-1990013604-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-15 WO disclosed
US-4908436-A Reactive dyes CIBA-GEIGY CORPORATION (US) 1990-03-13 US disclosed