SCHEMBL7803206

SCHEMBL7803206

O=S(=O)(CCCl)CC[N]c1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
CYP2D6 P10635 1/20 0.42
ATIC P31939 1/20 0.38
LMNA P02545 1/20 0.37
RPS6KA3 P51812 1/20 0.37
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36
NT5E P21589 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
GLO1 Q04760 1/20 0.32
PHLPP2 Q6ZVD8 1/20 0.32
NPC1 O15118 1/20 0.30
RECQL P46063 1/20 0.30
RAB9A P51151 1/20 0.30
ING2 Q9H160 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7803208 0.91 POLB (0.40) POLBCYP2D6ATICLMNARPS6KA3
SCHEMBL7803303 0.82 SENP3 (0.41) POLBCYP2D6ATICTSHRALDH1A1
SCHEMBL7840304 0.81 ALDH1A1 (0.33) CYP2D6ALDH1A1MEN1KMT2ATDP1
SCHEMBL7801205 0.80 CA2 (0.32) POLBCYP2D6LMNAALDH1A1MEN1
SCHEMBL7841062 0.76 PTGS2 (0.41) LMNAALDH1A1MEN1KMT2A
SCHEMBL7843599 0.75 TDP1 (0.46) POLBCYP2D6ATICLMNARPS6KA3
SCHEMBL7839508 0.74 TDP1 (0.37) POLBCYP2D6TSHRALDH1A1SMN1; SMN2
SCHEMBL2447623 0.73 CYP2D6 (0.52) POLBCYP2D6ATICLMNARPS6KA3
SCHEMBL7828787 0.72 ALDH1A1 (0.31) ALDH1A1MEN1KMT2A
SCHEMBL7843420 0.71 PRMT1 (0.39) LMNATSHRALDH1A1NT5ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0675172-B1 Water-solable azo compounds, process for their preparation and their use as dyestuffs DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-04-11 EP disclosed
EP-0688831-B1 Watersoluble anthraquinone compounds, process for their manufacturing and their use as dyestuffs DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-04-04 EP disclosed
US-5770709-A BRILLIANT COLOR SHADES, GOOD FASTNESS DURING USE AT HIGH DEGREE OF FIXING DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) 1998-06-23 US disclosed
EP-0538785-B1 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AG (DE) 1997-04-09 EP disclosed
US-5610298-A Water-soluble anthraquinone compounds, preparation thereof and use thereof as dyes HOECHST AKTIENGESELLSCHAFT (DE) 1997-03-11 US disclosed
EP-0703906-A4 FIBER REACTIVE ANTHRAQUINONE DYES HOECHST CELANESE CORP (US) 1996-08-28 EP disclosed
US-5539088-A PROVIDE DYEINGS IN BRILLIANT SHADES WITH GOOD FASTNESS PROPERTIES AND HIGH DEGREE OF FIXATION HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-23 US disclosed
US-5539109-A Fiber-reactive triphenodioxazine dyes HOECHST CELANESE CORPORATION (US) 1996-07-23 US disclosed
EP-0703906-A1 FIBER REACTIVE ANTHRAQUINONE DYES HOECHST CELANESE CORPORATION (US) 1996-04-03 EP disclosed
EP-0688831-A1 Watersoluble anthraquinone compounds, process for their manufacturing and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-27 EP disclosed
US-5280110-A Fiber-reactive dye HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-18 US disclosed
EP-0471702-B1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AG (DE) 1993-12-29 EP disclosed
US-5256776-A Brilliant green dyeings; fiber reactive HOECHST AKTIENGESELLSCHAFT (DE) 1993-10-26 US disclosed
US-5231172-A Water solubility HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-27 US disclosed
US-5227475-A WATER-SOLUBLE FIBER-REACTIVE DYESTUFFS CONTAINING A CYANAMIDO-SUBSTITUTED TRIAZINYLAMINO-GROUPING, AND A PROCESS FOR DYEING WITH THE USE OF THESE DYES HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-13 US disclosed
EP-0548792-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0538785-A2 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-28 EP disclosed
EP-0530660-A2 Water-soluble phthalocyanine dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-10 EP disclosed
EP-0527441-A2 Water-soluble phthalocyanine dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-02-17 EP disclosed
WO-1990013604-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-15 WO disclosed