Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801233 | 0.85 | CTSD (0.49) | CTSDBACE1 | |
| SCHEMBL7806328 | 0.81 | HTRA1 (0.51) | — | |
| SCHEMBL8736745 | 0.80 | CTSD (0.61) | CTSD | |
| SCHEMBL6556305 | 0.75 | ATM (0.54) | BACE1 | |
| SCHEMBL6556306 | 0.75 | ATM (0.54) | BACE1 | |
| SCHEMBL7807985 | 0.75 | CTSD (0.56) | CTSD | |
| SCHEMBL7807979 | 0.74 | TRPM8 (0.56) | CTSD | |
| SCHEMBL7323581 | 0.73 | TRPM8 (0.55) | CTSD | |
| SCHEMBL7269992 | 0.73 | CTSD (0.61) | CTSDBACE1 | |
| SCHEMBL9081107 | 0.71 | REN (0.49) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721449-B1 | INHIBITORS OF BETA-AMYLOID PROTEIN PRODUCTION | MERRELL PHARMA INC (US) | 2001-12-19 | — | — | EP | disclosed |
| US-5977074-A | THERAPY FOR ALZHEIMER'S DISEASE | MERRELL PHARMACEUTICALS, INC. (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0721449-A1 | INHIBITORS OF $g(b)-AMYLOID PROTEIN PRODUCTION | MERRELL PHARMACEUTICALS INC. (US) | 1996-07-17 | — | — | EP | disclosed |
| WO-1995009838-A1 | INHIBITORS OF β-AMYLOID PROTEIN PRODUCTION | MERRELL PHARMACEUTICALS INC. (US) | 1995-04-13 | — | — | WO | disclosed |