Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 7/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809241 | 0.86 | CTSD (0.55) | CTSKCTSLCTSSCTSBTACR1 | |
| SCHEMBL8736216 | 0.81 | CTSD (0.53) | CTSKCTSS | |
| SCHEMBL8196072 | 0.80 | TACR1 (0.61) | CTSKCTSLCTSSCTSBTACR1 | |
| SCHEMBL8361282 | 0.77 | CTSD (0.47) | CTSKCTSB | |
| SCHEMBL7283767 | 0.77 | ELANE (0.53) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7806325 | 0.76 | CMA1 (0.49) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7806366 | 0.76 | CTSL (0.47) | CTSKCTSLCTSSCTSBTACR1 | |
| SCHEMBL8492203 | 0.76 | CTSD (0.54) | CTSKCTSLCTSSCTSBTACR1 | |
| SCHEMBL7762796 | 0.76 | CTSL (0.74) | CTSKCTSLCTSSCTSBTACR1 | |
| SCHEMBL18071131 | 0.74 | CTSL (0.64) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721449-B1 | INHIBITORS OF BETA-AMYLOID PROTEIN PRODUCTION | MERRELL PHARMA INC (US) | 2001-12-19 | — | — | EP | claimed |