Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CMA1 | P23946 | 3/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.45 |
| ▸ | CTRC | Q99895 | 2/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.44 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.44 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.44 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.44 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806366 | 0.90 | CTSL (0.47) | CTSDCTSLCTSSCTSBCTSK | |
| SCHEMBL7801243 | 0.86 | CTSK (0.52) | CTSLCTSSCTSBCTSKTACR1 | |
| SCHEMBL8736216 | 0.83 | CTSD (0.53) | CTSDCTSSCTSKCMA1PSMB1 | |
| SCHEMBL7419140 | 0.82 | CTSL (0.48) | CTSDCTSLCTSSCTSBCTSK | |
| SCHEMBL7424510 | 0.82 | CTSL (0.48) | CTSDCTSLCTSSCTSBCTSK | |
| SCHEMBL7283767 | 0.79 | ELANE (0.53) | CTSDCTSLCTSSCTSBCTSK | |
| SCHEMBL7806325 | 0.79 | CMA1 (0.49) | CTSDCTSLCTSSCTSBCTSK | |
| SCHEMBL8361286 | 0.79 | CTSD (0.47) | CTSDCTSLCTSSCTSBCTSK | |
| SCHEMBL8361282 | 0.78 | CTSD (0.47) | CTSDCTSBCTSKCMA1ALDH1A1 | |
| SCHEMBL8364492 | 0.78 | CTSD (0.48) | CTSDCMA1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721449-B1 | INHIBITORS OF BETA-AMYLOID PROTEIN PRODUCTION | MERRELL PHARMA INC (US) | 2001-12-19 | — | — | EP | claimed |