Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809241 | 0.90 | CTSD (0.55) | CTSLCTSSCTSBCTSKCTSD | |
| SCHEMBL7806325 | 0.89 | CMA1 (0.49) | CTSLCTSSCTSBCTSKCTSD | |
| SCHEMBL8945318 | 0.84 | CTSD (0.46) | CTSLCTSSCTSKCTSDCMA1 | |
| SCHEMBL7419140 | 0.80 | CTSL (0.48) | CTSLCTSSCTSBCTSKCTSD | |
| SCHEMBL7424510 | 0.80 | CTSL (0.48) | CTSLCTSSCTSBCTSKCTSD | |
| SCHEMBL7801243 | 0.76 | CTSK (0.52) | CTSLCTSSCTSBCTSKTACR1 | |
| SCHEMBL7801249 | 0.76 | CASP3 (0.46) | CTSLCTSSCTSBCTSKCTSD | |
| SCHEMBL30431747 | 0.75 | SYK (0.49) | CTSLCTSSCTSBCTSKCTSD | |
| SCHEMBL8492203 | 0.74 | CTSD (0.54) | CTSLCTSSCTSBCTSKCTSD | |
| SCHEMBL8196072 | 0.74 | TACR1 (0.61) | CTSLCTSSCTSBCTSKTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721449-B1 | INHIBITORS OF BETA-AMYLOID PROTEIN PRODUCTION | MERRELL PHARMA INC (US) | 2001-12-19 | — | — | EP | claimed |