Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30860229 | 0.88 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTNPC1GPR119 | |
| SCHEMBL19127895 | 0.87 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTTGFBR1GPR119 | |
| SCHEMBL7805964 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTNR1D1TGFBR1 | |
| SCHEMBL31591498 | 0.81 | DRD2 (0.40) | ALDH1A1LMNAMAPTNPC1GPR119 | |
| SCHEMBL3352923 | 0.80 | GPR119 (0.58) | ALDH1A1LMNAMAPTGPR119 | |
| SCHEMBL3384221 | 0.78 | GLS (0.50) | LMNAMAPTNPC1 | |
| SCHEMBL7804911 | 0.77 | GPR119 (0.47) | ALDH1A1LMNAMAPTNPC1NR1D1 | |
| SCHEMBL31129835 | 0.77 | MET (0.37) | ALDH1A1LMNAMAPTPIK3CDGPR119 | |
| SCHEMBL28167461 | 0.76 | TSHR (0.51) | LMNAPIK3CDGPR119KDM4EPKM | |
| SCHEMBL7805916 | 0.76 | BRD4 (0.43) | ALDH1A1LMNAMAPTNPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| US-6046205-A | FOR TREATMENT OF VENOUS INSUFFICIENCY AND OF ASSOCIATED DISORDERS, AND ALSO IN THE TREATMENT OF MIGRAINE | ADIR ET COMPAGNIE (FR) | 2000-04-04 | — | — | US | disclosed |
| US-6020336-A | Indole and indazole compounds | LES LABORATOIRES SERVIER (FR) | 2000-02-01 | — | — | US | disclosed |