Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 1.00 |
| ▸ | SENP2 | Q9HC62 | 5/20 | 0.76 |
| ▸ | SENP1 | Q9P0U3 | 5/20 | 0.76 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.76 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.76 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.76 |
| ▸ | SENP3 | Q9H4L4 | 3/20 | 0.76 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | THRB | P10828 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | RECQL | P46063 | 3/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14418367 | 1.00 | ENPP2 (1.00) | ENPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL14418523 | 0.87 | SUMO2 (1.00) | ENPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL29374866 | 0.87 | SUMO2 (1.00) | ENPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL19154084 | 0.85 | SENP2 (0.79) | ENPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL11922531 | 0.85 | SENP2 (0.79) | ENPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL19132211 | 0.81 | SENP2 (0.69) | ENPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL19132261 | 0.81 | SENP2 (0.78) | ENPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL14413371 | 0.79 | SUMO2 (0.86) | ENPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL4952032 | 0.79 | SUMO2 (0.86) | ENPP2SENP2SENP1SUMO2SUMO1 | |
| SCHEMBL23787708 | 0.78 | SENP2 (0.74) | ENPP2SENP2SENP1SUMO2SUMO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010094-A4 | COMPOUND SCREENING SYSTEM | COMMW SCIENT IND RES ORG (AU) | 2001-03-07 | — | — | EP | disclosed |
| EP-1010094-A1 | COMPOUND SCREENING SYSTEM | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999012118-A1 | COMPOUND SCREENING SYSTEM | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1999-03-11 | — | — | WO | disclosed |