SCHEMBL7804685

SCHEMBL7804685

Cc1c(C(c2ccccc2O)c2ccc(O)c(-c3cccc(C4CCCCC4)c3)c2C)ccc(O)c1-c1cccc(C2CCCCC2)c1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
KMO O15229 1/20 0.36
ACMSD Q8TDX5 2/20 0.36
CTSS P25774 2/20 0.32
CTSK P43235 2/20 0.32
PDE2A O00408 1/20 0.32
ROCK2 O75116 1/20 0.31
PTPN5 P54829 2/20 0.30
PTPN2 P17706 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29375107 0.78 ACMSD (0.49) HDAC4HDAC2HDAC8KMOACMSD
SCHEMBL760436 0.78 ACMSD (0.49) HDAC4HDAC2HDAC8KMOACMSD
SCHEMBL29558450 0.77 GABRA1 (0.36) HDAC4HDAC2HDAC8ACMSD
SCHEMBL28717708 0.77 GABRA1 (0.36) HDAC4HDAC2HDAC8ACMSD
SCHEMBL2312929 0.76 HDAC4 (0.43) HDAC4HDAC2HDAC8KMOACMSD
SCHEMBL7804682 0.74 NUDT1 (0.37) HDAC4HDAC2HDAC8PTPN5PTPN2
SCHEMBL7804684 0.71 NUDT1 (0.39) HDAC4HDAC2HDAC8
SCHEMBL9135740 0.70 GABRA1 (0.34) HDAC4HDAC2HDAC8PTPN5PTPN2
SCHEMBL9138960 0.70 GABRA1 (0.34) HDAC4HDAC2HDAC8PTPN5PTPN2
SCHEMBL2530090 0.70 HDAC4 (0.39) HDAC4HDAC2HDAC8KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316170-B2 COATING, EXPOSURE, DEVELOPMENT AND HEAT TREATMENT KABUSHIKI KAISHA TOSHIBA (JP) 2001-11-13 US disclosed
US-20010006767-A1 Developing solution and method of forming polyimide pattern by using the developing solution YOSHIAKI KAWAMONZEN 2001-07-05 US disclosed