Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812670 | 0.85 | GPR88 (0.32) | MEN1TSHRKMT2AMMP3 | |
| SCHEMBL6982555 | 0.83 | ECE1 (0.33) | — | |
| SCHEMBL6981382 | 0.83 | REN (0.32) | MMP3 | |
| SCHEMBL7805709 | 0.80 | GPR88 (0.34) | MMP3 | |
| SCHEMBL7815484 | 0.78 | MMP8 (0.31) | — | |
| SCHEMBL6983030 | 0.78 | MMP1 (0.32) | MMP3 | |
| SCHEMBL6982283 | 0.77 | REN (0.36) | MMP3 | |
| SCHEMBL7805787 | 0.75 | TDP1 (0.32) | MEN1KMT2A | |
| SCHEMBL6986852 | 0.75 | EPHX2 (0.32) | MEN1TSHRKMT2AMMP3 | |
| SCHEMBL6983113 | 0.74 | CYP1A2 (0.36) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089964-A1 | HYDRAZINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000000465-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-01-06 | — | — | WO | disclosed |