Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP7 | P09237 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | BCL9 | O00512 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7800320 | 0.91 | MMP1 (0.38) | CHRM1CHRM5CHRM3MMP1MMP3 | |
| SCHEMBL7805589 | 0.85 | CHRM1 (0.38) | CHRM1CHRM5CHRM3MMP1MMP3 | |
| SCHEMBL7805486 | 0.83 | P2RX4 (0.41) | CHRM1CHRM5CHRM3MMP1MMP3 | |
| SCHEMBL7809176 | 0.82 | HCRTR2 (0.41) | CHRM1CHRM5CHRM3MMP1MMP3 | |
| SCHEMBL7805571 | 0.82 | KIF11 (0.40) | CHRM1CHRM5CHRM3MMP1MMP3 | |
| Acetic Acid SCHEMBL7809331 | 0.80 | ALDH1A1 (0.39) | CHRM1CHRM5CHRM3MMP1MMP3 | |
| SCHEMBL7805536 | 0.80 | CA1 (0.43) | MMP1MMP3MMP7MMP9MMP13 | |
| SCHEMBL7811618 | 0.78 | ALDH1A1 (0.42) | CHRM1CHRM5CHRM3MMP1MMP3 | |
| SCHEMBL7806847 | 0.78 | POLB (0.38) | MMP9ALDH1A1NPSR1TP53MMP2 | |
| SCHEMBL5409777 | 0.73 | BDKRB2 (0.41) | NPSR1POLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528678-B1 | A pyrrolidylthiocarbapenem derivative with antibacterial activity | SHIONOGI & CO (JP) | 2001-05-23 | — | — | EP | disclosed |
| US-5317016-A | Pyrrolidylthiocarbapenem derivative | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-05-31 | — | — | US | disclosed |