Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 6/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AGER | Q15109 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563153 | 0.78 | HTR7 (0.56) | SMN1; SMN2ALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL7755736 | 0.71 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CMAPTMAOA | |
| SCHEMBL7756348 | 0.67 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CMAPTMAOA | |
| SCHEMBL6560509 | 0.65 | KDM4A (0.51) | MAPTSMN1; SMN2ALDH1A1HPGDTSHR | |
| SCHEMBL7807464 | 0.65 | ENPP1 (0.44) | ADRA2AADRA2BADRA2CMAOAMAOB | |
| SCHEMBL10691844 | 0.64 | SMN1; SMN2 (0.45) | MAPTSMN1; SMN2TP53ALDH1A1HPGD | |
| SCHEMBL458419 | 0.62 | NPC1 (0.46) | MAPTSMN1; SMN2TP53ALDH1A1HPGD | |
| SCHEMBL7807451 | 0.62 | ADRA2A (0.53) | ADRA2AADRA2BADRA2CSMN1; SMN2ALDH1A1 | |
| SCHEMBL17279827 | 0.59 | GRM5 (0.48) | MAPTSMN1; SMN2TP53ALDH1A1HPGD | |
| SCHEMBL6561335 | 0.59 | HTR7 (0.52) | MAPTSMN1; SMN2ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071670-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054314-A1 | NOVEL DIPHENYL-SUBSTITUTED 5-RING-HETEROCYCLES, METHOD FOR PRODUCING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |