SCHEMBL7806928

SCHEMBL7806928

C=C/C=C\C(=C/C)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL259454 1.00 LMNA (0.30) LMNA
SCHEMBL22292169 0.82 ALDH1A1 (0.30)
SCHEMBL18657388 0.82 ALDH1A1 (0.30)
SCHEMBL18636925 0.81
SCHEMBL18389724 0.80 LMNA (0.30) LMNA
SCHEMBL2737129 0.80 ALDH1A1 (0.35)
SCHEMBL28298539 0.80 LMNA (0.30) LMNA
SCHEMBL28773027 0.78 ALDH1A1 (0.33)
SCHEMBL27092734 0.78 LMNA (0.35) LMNA
SCHEMBL26517720 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024071860-A1 INK COMPOSITION, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR 주식회사 엘지화학 2024-04-04 WO disclosed
US-10668090-B2 Liver specific delivery-based antiviral prodrug nucleoside cyclophosphate compound and uses thereof ZHEJIANG PALO ALTO PHARMACEUTICALS, INC (CN) 2020-06-02 US disclosed
EP-3604381-A1 THERMOPLASTIC LIQUID CRYSTAL POLYMER AND FILM OF SAME Kuraray Co., Ltd. (JP) 2020-02-05 EP disclosed
US-20190125771-A1 LIVER SPECIFIC DELIVERY-BASED ANTIVIRAL PRODRUG NUCLEOSIDE CYCLOPHOSPHATE COMPOUND AND USES THEREOF ZHEJIANG PALO ALTO PHARMACEUTICALS,INC (CN) 2019-05-02 US disclosed
US-20170137384-A1 PROCESS FOR THE PREPARATION OF KINASE INHIBITORS AND INTERMEDIATES THEREOF ALCON INC. (CH) 2017-05-18 US disclosed
US-20170049765-A1 Methylphenidate-Prodrugs, Processes of Making and Using the Same COMMAVE THERAPEUTICS SA (CH) 2017-02-23 US disclosed
US-9556294-B2 Magnetic particle-polymer hybrid materials with functionalized polymers derived from norbornenyl reagents THE UNIVERSITY OF KANSAS (US) 2017-01-31 US disclosed
US-20170020829-A1 Chemosensory Receptor Ligand-Based Therapies ANJI PHARMACEUTICALS INC. 2017-01-26 US disclosed
US-9463170-B2 Chemosensory receptor ligand-based therapies ELCELYX THERAPEUTICS, INC. (US) 2016-10-11 US disclosed
US-9453037-B2 Methylphenidate-prodrugs, processes of making and using the same KEMPHARM, INC (US) 2016-09-27 US disclosed
US-9050292-B2 Chemosensory receptor ligand-based therapies ELCELYX THERAPEUTICS, INC. (US) 2015-06-09 US disclosed
US-20140243291-A1 METHYLPHENIDATE-OXOACID CONJUGATES, PROCESSES OF MAKING AND USING THE SAME COMMAVE THERAPEUTICS SA (CH) 2014-08-28 US disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 US disclosed
US-20140030332-A1 Chemosensory Receptor Ligand-Based Therapies ELCELYX THERAPEUTICS, INC. (US) 2014-01-30 US disclosed
US-8426102-B2 Lithographic printing plate precursor and plate making method FUJIFILM CORPORATION (JP) 2013-04-23 US disclosed
EP-2404890-A1 Hydroxyl compounds and compositions for cholesterol management and related uses Esperion Therapeutics Inc. (US) 2012-01-11 EP disclosed
WO-2011145035-A1 NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES INDIAN INCOZEN THERAPEUTICS PVT. LTD. (IN) 2011-11-24 WO disclosed
WO-2010132852-A2 PROTEASE INHIBITORS AMPLYX PHARMACEUTICALS INC. (US) 2010-11-18 WO disclosed
EP-2011643-B1 Planographic printing plate precursor and printing method using the same FUJIFILM CORP (JP) 2010-10-13 EP disclosed
US-20080119517-A1 COMPOSITIONS AND METHODS FOR PROTECTING AGAINST MITOCHONDRIA COMPONENT-MEDIATED PATHOLOGY CORNELL RESEARCH FOUNDATION, INC. (US) 2008-05-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170137384-A1 PROCESS FOR THE PREPARATION OF KINASE INHIBITORS AND INTERMEDIATES THEREOF MAP3K1, MAP3K6, MAP3K7 LMNA 1106/4885
US-20190125771-A1 LIVER SPECIFIC DELIVERY-BASED ANTIVIRAL PRODRUG NUCLEOSIDE CYCLOPHOSPHATE COMPOUND AND USES THEREOF SLC10A1, NPC1, NPC1L1 LMNA 2438/4885
US-20140243291-A1 METHYLPHENIDATE-OXOACID CONJUGATES, PROCESSES OF MAKING AND USING THE SAME COMT, PNMT, SLC6A3 LMNA 4331/4885
US-20170049765-A1 Methylphenidate-Prodrugs, Processes of Making and Using the Same COMT, TPMT, PNMT LMNA 4533/4885
US-20170020829-A1 Chemosensory Receptor Ligand-Based Therapies TAS1R2, TAS2R1, GPR119 LMNA 3720/4885
US-10668090-B2 Liver specific delivery-based antiviral prodrug nucleoside cyclophosphate compound and uses thereof SLC10A1, NPC1, NPC1L1 LMNA 2438/4885
US-20140030332-A1 Chemosensory Receptor Ligand-Based Therapies TAS1R2, TAS2R1, GPR119 LMNA 3720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.