Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799285 | 0.83 | GBA1 (0.35) | OPRM1OPRD1 | |
| SCHEMBL22943654 | 0.81 | SIGMAR1 (0.33) | — | |
| SCHEMBL7808250 | 0.78 | MAPK1 (0.41) | LMNAOPRM1OPRD1CYP2D6CYP2C19 | |
| SCHEMBL7805881 | 0.74 | ACHE (0.35) | OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL7805841 | 0.71 | SIGMAR1 (0.35) | — | |
| SCHEMBL1114394 | 0.70 | MAPK1 (0.41) | LMNASLC6A3 | |
| SCHEMBL26157415 | 0.70 | LMNA (0.39) | LMNACYP2D6CYP2C19SLC6A3 | |
| SCHEMBL8718840 | 0.70 | ALDH1A1 (0.33) | — | |
| SCHEMBL7806697 | 0.70 | SIGMAR1 (0.34) | OPRM1OPRD1 | |
| SCHEMBL7805796 | 0.69 | LMNA (0.38) | LMNACYP2D6CYP2C19SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710662-B1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | SYNGENTA LTD (GB) | 2001-04-04 | — | — | EP | disclosed |
| EP-1018513-A2 | Quinolinecarboxylic acid derivatives | ZENECA LIMITED (GB) | 2000-07-12 | — | — | EP | disclosed |
| EP-0710662-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-05-08 | — | — | EP | disclosed |